5 edition of Experimental Headaches Models (Frontiers in Headache Research) found in the catalog.
by Raven Pr
Written in English
|Contributions||Jes Olesen (Editor), Michael A. Moskowitz (Editor)|
|The Physical Object|
|Number of Pages||358|
ISBN: OCLC Number: Description: x, pages: illustrations ; 27 cm: Contents: Methodological and theoretical issues in experimental modeling of anxiety in animals / Leandro José Bertoglio and Antônio de Pádua Carobrez --A standardized behavioral test battery to identify and validate targets for neuropsychiatric diseases and pain / Vladimir M. Pogorelov. Background: Cluster headache (CH), like migraine, is still regarded as a vascular headache although in both conditions a CNS cause has been suggested. Objective: To examine neurovascular mechanisms in CH. Methods: The authors used functional imaging with PET to investigate 18 CH patients (25 to 62 years old). Ten were in the active period (nine patients with induced attacks .
His research interests include experimental migraine and cluster headache models, neuroimaging, novel antimigraine drug targets, mechanism of migraine and action of antimigraine medications. He has authored over papers, abstracts and book chapters on the topic of headache, including migraine and cluster headache. This is the OG text on experimental design, and any data scientist who does a lot of experimentation will benefit from reading through it. We feel it's not the best possible experimental design book because it doesn't work as well as a reference as our top pick, and it tries to be too many things: an introductory statistics book, an.
The book presents reproducible experimental approach using animal models for human diseases with measurable equivalence to that of humans. It also presents models of high human predictive value. Despite the current insights and promising technologies, no scientific method can at this time fully address the limitation(s) of using animal models. Experimental Animal Models of Human Diseases - An Effective Therapeutic Strategy. Edited by: Ibeh Bartholomew. ISBN , eISBN , PDF ISBN , Published
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Series: Frontiers Experimental Headaches Models book Headache Research; Hardcover: pages; Publisher: Raven Pr (September 1, ) Language: English; ISBN ; ISBN ; Product Dimensions: x x inches Shipping Weight: pounds.
This text presents in-depth coverage of all the experimental models of headache disorders presently being used or developed. It covers all aspects of this valuable research area, including guidelines for the general use of models in drug development.
edited by Jes Olesen and Michael Moskowitz, pp., ill., Philadelphia, Lippincott-Raven, This volume in the Frontiers in Headache Research series presents results and discussions from the Fifth International Headache Research Seminar, held Author: Stewart J.
Tepper. The Headaches. Jes Olesen. Lippincott Williams & Wilkins, - Medical - pages. 1 Review. Established worldwide as the one definitive, encyclopedic reference on headache, The Headaches is 5/5(1). The goal of the study was to develop and validate a model of cutaneous allodynia triggered by dural inflammation for this aspect of pain associated with headaches.
Inflammatory mediators (IM) were applied to the dura of non-anesthetized rats via previously implanted cannulas and sensory thresholds of the face and hindpaws were by: About this book. This book provides essential insights into the current state of knowledge regarding the main aspects of cluster headache and trigeminal autonomic cephalgias.
The first chapters focus on classification and clinical features, together with familial and genetic aspects. Relevant animal models and the putative role of key nervous structures as the hypothalamus, brainstem, diencephalon and.
A powerful method to study primary headaches is using pharmacological triggers, which mimic endogenous triggers, to induce headache in humans. This chapter will describe and discuss established knowledge on human models of primary headache.
Experimental headache models in animals and humans lms Edvinsson Migraine and other forms of primary headaches have recently become of major interest to neuroscientists. The search for new approaches for treat- ment has concentrated on the charac- terization and cloning of 5-HT recep. In this context, experimental models based on the use of chemicals as nitroglycerin or inflammatory soup were extensively used to mimic the acute state and the chronicity of the disorder.
This manuscript is aimed to provide an overview of murine models used to investigate migraine pathophysiology. Describe 3 different animal models of migraine and other headaches Explain the importance of clinically-relevant outcome measurements when using animal models Discuss some of the advantages and limitations of animal models to study headache.
Experimental Models of Diabetes book. Experimental Models of Diabetes. DOI link for Experimental Models of Diabetes. Experimental Models of Diabetes book. Edited By John H. McNeill. Edition 1st Edition. First Published eBook Published 11 May Pub.
location New York. Imprint Routledge. Evidence gained from key molecules such as CGRP in animals and human headache models are discussed.
The book subsequently presents information on the various aspects of the pathophysiology of trigeminal autonomic cephalalgias for example regarding the implication of the trigeminovascular system and the facial autonomic reflexes of the brainstem Reviews: 1.
Moreover, participants will acquire knowledge about existing in vitro and in vivo experimental headache models. Communication based on a well-balanced scientific background Participants will learn to understand, discuss and critically assess the scientific literature.
Mixed Models A exible approach to correlated data. Overview Correlated data arise frequently in statistical analyses. This may be due to group-ing of subjects, e.g., students within classrooms, or to repeated measurements on each subject over time or space.
NTG is suitable as an experimental headache model. A constant infusion of microgram/kg/min will be suitable for studies of arterial diameter, pulsations, blood flow, etc. Comparative studies of sensitivity should use the present infusion schedule but with the two highest doses substituted by and microgram/kg/min.
Book chapter Full text access Chapter 11 - Implementing the International Classification of Headache Disorders, 2nd edition (ICHD-II) Timothy J. Steiner, Jes Olesen. The need for valid human experimental models of headache is obvious.
Several compounds have been proposed as headache-inducing agents, but only the nitroglycerin (NTG) model has been validated. In healthy subjects, intravenous infusions of the nitric oxide (NO) donor NTG induce a dose-dependent headache and dilatation of the temporal, radial.
Behavioral and cognitive animal models in headache research. Animal models have provided a growing body of information about the pathophysiology of headaches and novel therapeutic targets. In recent years, experiments in awake animals have gained attention as more relev Authors: Doga Vuralli, Anne-Sophie Wattiez, Andrew F.
Russo and Hayrunnisa Bolay. A First Course in Design and Analysis of Experiments Gary W. Oehlert University of Minnesota. Experimental headache models in animals and humans. Edvinsson L(1). Author information: (1)Department of Internal Medicine, University Hospital of Lund, Sweden.
The role of peripheral (muscular) factors is suggested on the basis of experimental models and aggravating factors in tension-type headache.
Prolonged muscular contraction and/or the activation of peripheral fibers could play an important role in the development of a typical central phenomenon: sensitization of the pain control system.Studies on man and lower animals have shown that the cranial blood vessels are pain-sensitive structures, capable under special circumstances of giving rise to headache.
1 The distention of cerebral arteries is primarily responsible for the headache produced by certain chemical agents, of which histamine is representative; 2 the headache associated with septicemia and fever is in the same.A.
Headache attacks lasting 2 to 72 hours (untreated or unsuccessfully treated) • Warnings, called auras, may start before the headache in up to 20% of migraine sufferers.
These auras can include blurry vision, flashing lights, spots, unilateral numbness, or unilateral sensory changes and.